Blogging this since this is hella useful that I know I’ll forget how to later.
The issue is, Visual Studio is nearly not as good a debugger as browsers are. And frequently I do want to debug C# (server side code), but not have Visual Studio debug JavaScript. Wish this was the default F5 behavior. But, with a simple checkbox, it can be.
Go to Tools\Options\Debugging\Just in time\Script <—uncheck that.